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KMID : 1143620170210020049
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Korean Journal of Nuclear Medicine Technology
2017 Volume.21 No. 2 p.49 ~ p.54
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The Study on the Dilution Time of Radioactive Tracer in Estradiol Measurement
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Lee Seung-Jae
Seo Soo-Hyun
Lee Sung-Ha
Park Yong-Sung
Oh Ki-Beak
Kim Jae-Sam
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Abstract
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Purpose : The high-dose administration of I-131 has been standing for the basic therapy method of thyroid cancer. In orea, it is not necessary for patients to be hospitalized if the administration dose are under 1.2 GBq. However, if the dose are over 1.2 GBq, the patients should be stay in special ward with radiation shield. In such cases, the radioactivity level upon release should be under a dose of 70 μSv/hr at a distance of approx. 1m. This regulation bring the patients to stay for about 2 to 3 days in ward before the release.
Materials and Methods : Using the inpatients’ release data of severance hospital, an inpatient-days were retrospectively calculated and compared with practical data and estimate the inpatient-days with the conditions of korea (70 μSv/hr), Japan (30 μSv/hr), germany (3.5 μSv/hr at a distance of approx. 2 m), and other european countries.
Results : When a effective half-life of 15.4 was used, the expected inpatient-days were calculated as 2.15 days in the condition of Japanese regulation and 1.37 days in the condition of korean regulation. The practical inpatient-days of patients in Severance hospital were 1.32 days.
Conclusion : As ICRP 94 has been mentioned that the release of patients administrated with I-131 for the therapy should be
carefully considered because each patients has different thyroid uptake rate and their conditions with family members after the release from the ward. Nonetheless, efforts to bring more aquate data which is for getting closer to the practical data should be continuously studied.
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KEYWORD
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Thyroid iodine therapy, Iodine-131 therapy
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